Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters
This study sought to develop a diagnostic model with aberrometry and biomechanical variables for subclinical keratoconus. The design was a cross-sectional study. The topographic data were obtained with a rotating Scheimpflug camera (Pentacam HR), and biomechanical data were obtained with Corvis ST....
| Main Authors: | , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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MDPI
2021
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| Online Access: | http://hdl.handle.net/10835/11974 |
| _version_ | 1789408402374393856 |
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| author | Pérez-Rueda, Antonio Jiménez-Rodríguez, Diana Castro-Luna, Gracia |
| author_facet | Pérez-Rueda, Antonio Jiménez-Rodríguez, Diana Castro-Luna, Gracia |
| author_sort | Pérez-Rueda, Antonio |
| collection | DSpace |
| description | This study sought to develop a diagnostic model with aberrometry and biomechanical variables for subclinical keratoconus. The design was a cross-sectional study. The topographic data were obtained with a rotating Scheimpflug camera (Pentacam HR), and biomechanical data were obtained with Corvis ST. The study included 81 eyes distributed in 61 healthy corneas and 20 subclinical keratoconus (SCKC), defined as eyes with suspicious topographic findings, normal slit-lamp examination, and a manifestation of keratoconus. Analyses of the topographic and biomechanical data were performed, and a classifying model of SCKC was elaborated. The model for the diagnosis of SCKC includes posterior coma to 90°, Ambrósio’s Relational Thickness in the horizontal profile (ARTh), and velocity when the air pulse is off (A2 velocity). The sensitivity was 89.5%, specificity 96.7%, accuracy 94.9%, and precision 89.5%. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve for the model was 0.951. Diagnosis of subclinical keratoconus depends on the aberrometry variable posterior coma to 90° and the biomechanical variables A2 velocity and ARTh. |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-11974 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2021 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-119742023-04-12T19:20:39Z Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters Pérez-Rueda, Antonio Jiménez-Rodríguez, Diana Castro-Luna, Gracia subclinical keratoconus topography biomechanics Corvis ST This study sought to develop a diagnostic model with aberrometry and biomechanical variables for subclinical keratoconus. The design was a cross-sectional study. The topographic data were obtained with a rotating Scheimpflug camera (Pentacam HR), and biomechanical data were obtained with Corvis ST. The study included 81 eyes distributed in 61 healthy corneas and 20 subclinical keratoconus (SCKC), defined as eyes with suspicious topographic findings, normal slit-lamp examination, and a manifestation of keratoconus. Analyses of the topographic and biomechanical data were performed, and a classifying model of SCKC was elaborated. The model for the diagnosis of SCKC includes posterior coma to 90°, Ambrósio’s Relational Thickness in the horizontal profile (ARTh), and velocity when the air pulse is off (A2 velocity). The sensitivity was 89.5%, specificity 96.7%, accuracy 94.9%, and precision 89.5%. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve for the model was 0.951. Diagnosis of subclinical keratoconus depends on the aberrometry variable posterior coma to 90° and the biomechanical variables A2 velocity and ARTh. 2021-07-21T07:44:35Z 2021-07-21T07:44:35Z 2021-06-22 info:eu-repo/semantics/article 2077-0383 http://hdl.handle.net/10835/11974 en https://www.mdpi.com/2077-0383/10/13/2746 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess MDPI |
| spellingShingle | subclinical keratoconus topography biomechanics Corvis ST Pérez-Rueda, Antonio Jiménez-Rodríguez, Diana Castro-Luna, Gracia Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters |
| title | Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters |
| title_full | Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters |
| title_fullStr | Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters |
| title_full_unstemmed | Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters |
| title_short | Diagnosis of Subclinical Keratoconus with a Combined Model of Biomechanical and Topographic Parameters |
| title_sort | diagnosis of subclinical keratoconus with a combined model of biomechanical and topographic parameters |
| topic | subclinical keratoconus topography biomechanics Corvis ST |
| url | http://hdl.handle.net/10835/11974 |
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