Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review
In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such...
| Main Authors: | , , , , , , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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MDPI
2021
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10835/12025 |
| _version_ | 1789406527952519168 |
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| author | Pinos, Helena Carrillo, Beatriz Merchán, Ana Biosca-Brull, Judit Pérez-Fernández, Cristian Colomina, María Teresa Sánchez-Santed, Fernando Martín-Sánchez, Fernando Collado, Paloma Arias, Jorge L. Conejo, Nélida M. |
| author_facet | Pinos, Helena Carrillo, Beatriz Merchán, Ana Biosca-Brull, Judit Pérez-Fernández, Cristian Colomina, María Teresa Sánchez-Santed, Fernando Martín-Sánchez, Fernando Collado, Paloma Arias, Jorge L. Conejo, Nélida M. |
| author_sort | Pinos, Helena |
| collection | DSpace |
| description | In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health. |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-12025 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2021 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-120252023-04-12T19:43:41Z Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review Pinos, Helena Carrillo, Beatriz Merchán, Ana Biosca-Brull, Judit Pérez-Fernández, Cristian Colomina, María Teresa Sánchez-Santed, Fernando Martín-Sánchez, Fernando Collado, Paloma Arias, Jorge L. Conejo, Nélida M. obesity pesticides organophosphate organochlorine chlorpyrifos carbamates pyrethroids neonicotinoids In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health. 2021-07-22T08:28:45Z 2021-07-22T08:28:45Z 2021-07-04 info:eu-repo/semantics/article 1660-4601 http://hdl.handle.net/10835/12025 en https://www.mdpi.com/1660-4601/18/13/7170 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess MDPI |
| spellingShingle | obesity pesticides organophosphate organochlorine chlorpyrifos carbamates pyrethroids neonicotinoids Pinos, Helena Carrillo, Beatriz Merchán, Ana Biosca-Brull, Judit Pérez-Fernández, Cristian Colomina, María Teresa Sánchez-Santed, Fernando Martín-Sánchez, Fernando Collado, Paloma Arias, Jorge L. Conejo, Nélida M. Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review |
| title | Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review |
| title_full | Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review |
| title_fullStr | Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review |
| title_full_unstemmed | Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review |
| title_short | Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review |
| title_sort | relationship between prenatal or postnatal exposure to pesticides and obesity: a systematic review |
| topic | obesity pesticides organophosphate organochlorine chlorpyrifos carbamates pyrethroids neonicotinoids |
| url | http://hdl.handle.net/10835/12025 |
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