Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study
The physiological changes during pregnancy may increase the risk of complications in pregnant women with coronavirus disease 2019 (COVID-19). Vitamin D is a fat-soluble secosteroid hormone and its role in immunity is appears to be of particular importance in this recent pandemic. Nevertheless, there...
| Main Authors: | , , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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MDPI
2022
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10835/13602 |
| _version_ | 1789408408081793024 |
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| author | Ferrer-Sánchez, Nazaret Díaz-Goicoechea, Marina Mayoral-Cesar, Victoria García-Solbas, Silvia Nievas Soriano, Bruno José Parrón Carreño, Tesifón Fernández Alonso, Ana María |
| author_facet | Ferrer-Sánchez, Nazaret Díaz-Goicoechea, Marina Mayoral-Cesar, Victoria García-Solbas, Silvia Nievas Soriano, Bruno José Parrón Carreño, Tesifón Fernández Alonso, Ana María |
| author_sort | Ferrer-Sánchez, Nazaret |
| collection | DSpace |
| description | The physiological changes during pregnancy may increase the risk of complications in pregnant women with coronavirus disease 2019 (COVID-19). Vitamin D is a fat-soluble secosteroid hormone and its role in immunity is appears to be of particular importance in this recent pandemic. Nevertheless, there is little research about the role of vitamin D levels regarding COVID-19 in pregnant women to date. This study aimed to establish a relationship between serum 25-hydroxyvitamin D (25(OH)D) levels in pregnant women and COVID-19. A comparative case-control study was performed with a study population of 256 pregnant women (82 pregnant women with infection and 174 women in control group). Serum 25(OH)D levels were significantly lower in pregnant women with COVID-19 infection than in those without infection. In addition, 89% of COVID-19-positive pregnant women had 25(OH)D deficiency, while in the control group the percentage was 75.30%, finding statistically significant differences (ORa = 2.68; 95% CI 1.19–6.06; p = 0.01). Our results find a relationship between vitamin D deficiency in pregnant women and COVID-19 infection. This finding could be relevant for actual clinical practice. Thus, more research is needed in this field. |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-13602 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-136022023-04-12T19:19:34Z Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study Ferrer-Sánchez, Nazaret Díaz-Goicoechea, Marina Mayoral-Cesar, Victoria García-Solbas, Silvia Nievas Soriano, Bruno José Parrón Carreño, Tesifón Fernández Alonso, Ana María vitamin D COVID-19 coronavirus pregnant women The physiological changes during pregnancy may increase the risk of complications in pregnant women with coronavirus disease 2019 (COVID-19). Vitamin D is a fat-soluble secosteroid hormone and its role in immunity is appears to be of particular importance in this recent pandemic. Nevertheless, there is little research about the role of vitamin D levels regarding COVID-19 in pregnant women to date. This study aimed to establish a relationship between serum 25-hydroxyvitamin D (25(OH)D) levels in pregnant women and COVID-19. A comparative case-control study was performed with a study population of 256 pregnant women (82 pregnant women with infection and 174 women in control group). Serum 25(OH)D levels were significantly lower in pregnant women with COVID-19 infection than in those without infection. In addition, 89% of COVID-19-positive pregnant women had 25(OH)D deficiency, while in the control group the percentage was 75.30%, finding statistically significant differences (ORa = 2.68; 95% CI 1.19–6.06; p = 0.01). Our results find a relationship between vitamin D deficiency in pregnant women and COVID-19 infection. This finding could be relevant for actual clinical practice. Thus, more research is needed in this field. 2022-04-07T17:56:59Z 2022-04-07T17:56:59Z 2022-03-26 info:eu-repo/semantics/article 1660-4601 http://hdl.handle.net/10835/13602 10.3390/ijerph19073965 en https://www.mdpi.com/1660-4601/19/7/3965 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess MDPI |
| spellingShingle | vitamin D COVID-19 coronavirus pregnant women Ferrer-Sánchez, Nazaret Díaz-Goicoechea, Marina Mayoral-Cesar, Victoria García-Solbas, Silvia Nievas Soriano, Bruno José Parrón Carreño, Tesifón Fernández Alonso, Ana María Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study |
| title | Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study |
| title_full | Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study |
| title_fullStr | Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study |
| title_full_unstemmed | Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study |
| title_short | Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study |
| title_sort | serum 25(oh) vitamin d levels in pregnant women with coronavirus disease 2019 (covid-19): a case-control study |
| topic | vitamin D COVID-19 coronavirus pregnant women |
| url | http://hdl.handle.net/10835/13602 |
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