Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3
CpTiCl2, prepared in situ by manganese reduction of CpTiCl3, is an excellent new system for the Barbier-type allylation and propargylation of carbonyl compounds. It can be used in catalytic amounts when combined with Et3N•HBr/TMSBr, which act as regenerating system. The high regio- and stereoselecti...
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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American Chemical Society
2023
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| Online Access: | http://hdl.handle.net/10835/14713 https://doi.org/10.1021/acs.joc.8b02643 |
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| author | López Martínez, Josefa Leticia Torres García, Irene Rodríguez García, Ignacio Manuel Muñoz Dorado, Manuel Álvarez Corral, Míriam |
| author_facet | López Martínez, Josefa Leticia Torres García, Irene Rodríguez García, Ignacio Manuel Muñoz Dorado, Manuel Álvarez Corral, Míriam |
| author_sort | López Martínez, Josefa Leticia |
| collection | DSpace |
| description | CpTiCl2, prepared in situ by manganese reduction of CpTiCl3, is an excellent new system for the Barbier-type allylation and propargylation of carbonyl compounds. It can be used in catalytic amounts when combined with Et3N•HBr/TMSBr, which act as regenerating system. The high regio- and stereoselectivity shown by this system makes it useful for prenylation and crotylation processes in synthesis of natural products. |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-14713 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2023 |
| publisher | American Chemical Society |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-147132023-12-04T07:24:43Z Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 López Martínez, Josefa Leticia Torres García, Irene Rodríguez García, Ignacio Manuel Muñoz Dorado, Manuel Álvarez Corral, Míriam Organic Chemistry CpTiCl2, prepared in situ by manganese reduction of CpTiCl3, is an excellent new system for the Barbier-type allylation and propargylation of carbonyl compounds. It can be used in catalytic amounts when combined with Et3N•HBr/TMSBr, which act as regenerating system. The high regio- and stereoselectivity shown by this system makes it useful for prenylation and crotylation processes in synthesis of natural products. 2023-12-04T07:24:42Z 2023-12-04T07:24:42Z 2019 info:eu-repo/semantics/article J. Org. Chem. 2019, 84, 2, 806–816 http://hdl.handle.net/10835/14713 https://doi.org/10.1021/acs.joc.8b02643 en https://pubs.acs.org/doi/10.1021/acs.joc.8b02643 info:eu-repo/semantics/openAccess American Chemical Society This document is the Accepted Manuscript version of a Published Work that appeared in final form in [J. Org. Chem. 2019, 84, 2, 806–816], copyright © [Copyright © 2018 American Chemical Society] after peer review and technical editing by the publisher. To access the final edited and published work see [https://pubs.acs.org/doi/10.1021/acs.joc.8b02643] |
| spellingShingle | Organic Chemistry López Martínez, Josefa Leticia Torres García, Irene Rodríguez García, Ignacio Manuel Muñoz Dorado, Manuel Álvarez Corral, Míriam Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 |
| title | Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 |
| title_full | Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 |
| title_fullStr | Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 |
| title_full_unstemmed | Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 |
| title_short | Stereoselective Barbier Type Allylations and Propargylations Mediated by CpTiCl3 |
| title_sort | stereoselective barbier type allylations and propargylations mediated by cpticl3 |
| topic | Organic Chemistry |
| url | http://hdl.handle.net/10835/14713 https://doi.org/10.1021/acs.joc.8b02643 |
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