An integrated approach for the efficient separation of specialty compounds from biomass of the marine microalgae Amphidinium carterae

An amphidinol-prioritized fractioning approach was for the first time developed to isolate multiple specialty metabolites such as amphidinols, carotenoids and fatty acids using the biomass of the marine microalgae Amphidinium carterae. The biomass was produced in a raceway photobioreactor and the ex...

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Bibliographic Details
Main Authors: López Rodríguez, Mercedes, Cerón García, María Del Carmen, López Rosales, Lorenzo, Navarro López, Elvira, Sánchez Mirón, Asterio, Molina Miras, Alejandro, Abreu, A. C., Fernández De Las Nieves, Ignacio, García Camacho, Francisco
Format: info:eu-repo/semantics/article
Language:English
Published: Elsevier 2024
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Online Access:http://hdl.handle.net/10835/15222
https://doi.org/10.1016/j.biortech.2021.125922
Description
Summary:An amphidinol-prioritized fractioning approach was for the first time developed to isolate multiple specialty metabolites such as amphidinols, carotenoids and fatty acids using the biomass of the marine microalgae Amphidinium carterae. The biomass was produced in a raceway photobioreactor and the exhausted culture media were reused, thus fulfilling sustainability criteria employing a circular economy concept. The integrated bioactive compounds-targeted approach presented here consisted of four steps with which recovery percentages of carotenoids, fatty acids and amphidinols of 97%, 82% and 99 %, respectively, were achieved. The proposed process was proved to be a better extraction system for this microalga than another based on a sequential gradient partition with water and four water-immiscible organic solvents (hexane, carbon tetrachloride, dichloromethane and n-butanol). The proposed process could be scaled-up as a commercial solid-phase extraction technology well-established for industrial bioprocesses.