Designing Single-Molecule Magnets as Drugs with Dual Anti-Inflammatory and Anti-Diabetic Effects

Designing Single-Molecule Magnets as Drugs with Dual Anti-Inflammatory and Anti-Diabetic Effects

We have designed and synthesized two novel cobalt coordination compounds using bumetanide (bum) and indomethacin (ind) therapeutic agents. The anti-inflammatory effects of cobalt metal complexes with ind and bum were assayed in lipopolysaccharide stimulated RAW 264.7 macrophages by inhibition of nit...

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Bibliographic Details
Main Authors: Navas, Arturo, Jannus, Fatin, Fernández, Belén, Cepeda, Javier, Medina O’Donnell, Marta, Díaz Ruiz, Luis, Sánchez González, Cristina, Llopis Marín, Juan Manuel, Seco, José M., Rufino Palomares, E., Lupiáñez, José Antonio, Gómez Ruiz, Santiago, Quiles, José Luis, Battino, Maurizio, Choquesillo Lazarte, Duane, Ruiz Muelle, Ana Belén, Fernández de las Nieves, Ignacio, Reyes Zurita, Fernando, Rodríguez Diéguez, Antonio
Format: info:eu-repo/semantics/article
Language:English
Published: MDPI 2020
Subjects:
bumetadine
indomethacin
cobalt
coordination compound
single-ion magnet
inflammatory
diabetes
Online Access:http://hdl.handle.net/10835/8181

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