Age-Related Risk Factors at the First Stroke Event
(1) Background: Stroke is a multifactorial disease, which can affect individuals at any age. Risk factors (RFs) associated with the first stroke event have been well identified; however, the influence of these RFs on the patient’s age needs to be studied. (2) Objective: This study aimed to examine t...
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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MDPI
2020
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| Online Access: | http://hdl.handle.net/10835/8349 |
| _version_ | 1789406755767189504 |
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| author | Soto Cámara, Raúl González Bernal, Jerónimo J. González Santos, Josefa Aguilar Parra, José Manuel Trigueros Ramos, Rubén López Liria, Remedios |
| author_facet | Soto Cámara, Raúl González Bernal, Jerónimo J. González Santos, Josefa Aguilar Parra, José Manuel Trigueros Ramos, Rubén López Liria, Remedios |
| author_sort | Soto Cámara, Raúl |
| collection | DSpace |
| description | (1) Background: Stroke is a multifactorial disease, which can affect individuals at any age. Risk factors (RFs) associated with the first stroke event have been well identified; however, the influence of these RFs on the patient’s age needs to be studied. (2) Objective: This study aimed to examine the effect of modifiable RFs on the age at which a stroke occurs. (3) Methods: A cross-sectional study was conducted on patients admitted consecutively with a first-ever acute stroke at the Burgos University Hospital (Spain). Data on sociodemographic and clinical parameters were collected (high blood pressure (HBP), smoking habit, diabetes mellitus (DM), dyslipemia, abdominal obesity, sedentary lifestyle, alcohol consumption, and cardiovascular diseases). The possible associations between RFs and age were studied using univariate and multivariate regression analyses and a decision tree. (4) Results: A total of 436 patients with a mean age of 75.39 years (standard deviation (SD) ± 12.67) were included. HBP and overweight/obesity were the most prevalent stroke RFs. Being an active smoker (OR 21.48; 95% confidence interval (CI) 8.80–52.41), having a sedentary lifestyle (OR 3.24; 95% CI 1.97–5.31), being an excessive alcohol drinker (OR 2.36; 95% CI 1.45–3.84), or being overweight or obese (OR 1.95; 95% CI 1.14–3.34) increased the risk of having an acute cerebrovascular event in individuals aged 75 years or below. However, a personal history of HBP (OR 0.40; 95% CI 0.24–0.67) was significantly associated with a greater likelihood of having an acute stroke in individuals aged more than 75 years. (5) Conclusions: This study showed that the modifiable RFs strongly influence the first stroke event in patients aged below 75 years, which will be useful in guiding different prevention strategies. |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-8349 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2020 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-83492023-04-12T19:46:09Z Age-Related Risk Factors at the First Stroke Event Soto Cámara, Raúl González Bernal, Jerónimo J. González Santos, Josefa Aguilar Parra, José Manuel Trigueros Ramos, Rubén López Liria, Remedios stroke risk factors age elderly (1) Background: Stroke is a multifactorial disease, which can affect individuals at any age. Risk factors (RFs) associated with the first stroke event have been well identified; however, the influence of these RFs on the patient’s age needs to be studied. (2) Objective: This study aimed to examine the effect of modifiable RFs on the age at which a stroke occurs. (3) Methods: A cross-sectional study was conducted on patients admitted consecutively with a first-ever acute stroke at the Burgos University Hospital (Spain). Data on sociodemographic and clinical parameters were collected (high blood pressure (HBP), smoking habit, diabetes mellitus (DM), dyslipemia, abdominal obesity, sedentary lifestyle, alcohol consumption, and cardiovascular diseases). The possible associations between RFs and age were studied using univariate and multivariate regression analyses and a decision tree. (4) Results: A total of 436 patients with a mean age of 75.39 years (standard deviation (SD) ± 12.67) were included. HBP and overweight/obesity were the most prevalent stroke RFs. Being an active smoker (OR 21.48; 95% confidence interval (CI) 8.80–52.41), having a sedentary lifestyle (OR 3.24; 95% CI 1.97–5.31), being an excessive alcohol drinker (OR 2.36; 95% CI 1.45–3.84), or being overweight or obese (OR 1.95; 95% CI 1.14–3.34) increased the risk of having an acute cerebrovascular event in individuals aged 75 years or below. However, a personal history of HBP (OR 0.40; 95% CI 0.24–0.67) was significantly associated with a greater likelihood of having an acute stroke in individuals aged more than 75 years. (5) Conclusions: This study showed that the modifiable RFs strongly influence the first stroke event in patients aged below 75 years, which will be useful in guiding different prevention strategies. 2020-07-21T07:00:56Z 2020-07-21T07:00:56Z 2020-07-14 info:eu-repo/semantics/article 2077-0383 http://hdl.handle.net/10835/8349 en https://www.mdpi.com/2077-0383/9/7/2233 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess MDPI |
| spellingShingle | stroke risk factors age elderly Soto Cámara, Raúl González Bernal, Jerónimo J. González Santos, Josefa Aguilar Parra, José Manuel Trigueros Ramos, Rubén López Liria, Remedios Age-Related Risk Factors at the First Stroke Event |
| title | Age-Related Risk Factors at the First Stroke Event |
| title_full | Age-Related Risk Factors at the First Stroke Event |
| title_fullStr | Age-Related Risk Factors at the First Stroke Event |
| title_full_unstemmed | Age-Related Risk Factors at the First Stroke Event |
| title_short | Age-Related Risk Factors at the First Stroke Event |
| title_sort | age-related risk factors at the first stroke event |
| topic | stroke risk factors age elderly |
| url | http://hdl.handle.net/10835/8349 |
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