An Updated Focus on Quadruplex Structures as Potential Therapeutic Targets in Cancer

Non-canonical, four-stranded nucleic acids secondary structures are present within regulatory regions in the human genome and transcriptome. To date, these quadruplex structures include both DNA and RNA G-quadruplexes, formed in guanine-rich sequences, and i-Motifs, found in cytosine-rich sequences,...

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Détails bibliographiques
Auteurs principaux: Sanchez Martin, Victoria, Lopez Pujante, Carmen, Soriano Rodriguez, Miguel, Garcia Salcedo, Jose A.
Format: info:eu-repo/semantics/article
Langue:English
Publié: MDPI 2020
Sujets:
Accès en ligne:http://hdl.handle.net/10835/9032