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3by Laspidea, V. (Virginia), Alonso-Roldán, M.M. (Marta María), Patiño-García, A. (Ana)“…Therefore, the latter show much lower genetic aberrations. 3,4 The most frequently diagnosed tumors during childhood are hematological malignancies (including leukemia and lymphoma), followed by tumors of the central nervous system (CNS). Specifically, leukemia (24.7%), tumors of the central nervous system (17.2%), non-Hodgking lymphoma (7.5%), Hodgking lymphoma (6.5%), soft-tissue sarcoma (5.9%) and bone tumors (4-8%) are the most common groups5 (Figure 1). …”
Published 2023
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4by Arredondo-Montero, J. (Javier), Bronte-Anaut, M. (Mónica), Caballero, M.C. (M.C.), Fernández-Seara, M.P. (María del Pilar), Martin-Calvo, N. (Nerea)“…CMV inclusions were observed in the lung, liver, thyroid, pancreas, kidneys, adrenal, placenta, and central nervous system. Intracranial hemorrhage is a rare finding in the context of congenital CMV infection, with isolated brainstem hemorrhage being an exceptional form of presentation. …”
Published 2023
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5“…These channels are activated following the modulation of G-protein-coupled receptors and, although they have been implicated in different neurological diseases in both human and animal studies of the central nervous system, the therapeutic potential of different subtypes of these channel families in cardiac conditions has remained untapped. …”
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6by Sadaba, B. (Belén), Azanza, J.R. (José Ramón), Gomez-Guiu, A. (Almudena), Rodil, R. (R.)“…It is not distributed to the central nervous system, is scarcely metabolized, and elimination is through the kidneys and feces, with a 14-hour elimination half-life. …”
Published 2014
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7by Velayos, J.L. (José Luis), Irujo, A. (A.), Cuadrado-Tejedor, M. (Mar), Paternain, B. (B.), Moleres, F.J. (Francisco J.), Ferrer, V. (Vicente)“…The cellular prion protein (PrPC) is a membrane-bound glycoprotein especially abundant in the central nervous system (CNS). The scrapie prion protein (PrPSc, also termed prions) is responsible of transmissible spongiform encephalopathies (TSE), a group of neurodegenerative diseases which affect humans and other mammal species, although the presence of PrPC is needed for the establishment and further evolution of prions. …”
Published 2010
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10by Schalper, K.A. (Kurt A.), Rodriguez-Ruiz, M.E. (María Esperanza), Diez-Valle, R. (Ricardo), López-Janeiro, Á. (Álvaro), Porciuncula, A. (Angelo), Idoate, M.A. (Miguel Ángel), Inoges, S. (Susana), Andrea, C.E. (Carlos Eduardo) de, Lopez-Diaz-de-Cerio, A. (Ascensión), Tejada-Solis, S. (Sonia), Berraondo, P. (Pedro), Villarroel-Espindola, F. (Franz), Choi, J. (Jungmin), Gurpide, A. (Alfonso), Giraldez, M. (Miriam), Goicoechea, I. (Iosune), Gallego-Perez-Larraya, J. (Jaime), Fernandez-Sanmamed, M. (Miguel), Perez-Gracia, J.L. (Jose Luis), Melero, I. (Ignacio)“…Glioblastoma is the most common primary central nervous system malignancy and has a poor prognosis. …”
Published 2024
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11“…Glioma is a general term used to describe the primary brain tumors that are the most common in the central nervous system (CNS). Glioblastoma multiforme (GBM) is the most malignant type which constitutes more than 60% of all brain tumors in adults. …”
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13by Acanda-de-la-Rocha, A.M. (Arlet María), Alonso-Roldán, M.M. (Marta María), Martin-Algarra, S. (Salvador)“…It constitutes 45,2% of all malignant central nervous system (CNS) tumors and 80% of all primary malignant CNS tumors. …”
Published 2017
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14“…Recent research led by our group, reported some alterations in the central nervous system (CNS) such as decreased cerebral blood flow during porphyria crises and brain ventricle enlargement in patients suffering recurrent porphyria attacks. …”
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