Showing 1 - 18 results of 18 for search '"nucleotide"', query time: 0.05s Refine Results
  1. 1
    Interaction between genes and lifestyle factors on obesity.
    “…Common single-nucleotide polymorphisms at candidate genes for obesity may act as effect modifiers for environmental factors. …”
    Get full text
    info:eu-repo/semantics/article
  2. 2
    Plasmodium vivax Cysteine-Rich Protective Antigen Polymorphism at Exon-1 Shows Recombination and Signatures of Balancing Selection
    “…The nucleotide diversity and Tajima’s D values varied across the coding gene. …”
    Get full text
    info:eu-repo/semantics/article
  3. 3
    Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease
    “…In this work, the authors want to offer a brief overview of the different validated targets that are involved in diverse parasite pathways: glycolysis, sterol synthesis, the de novo biosynthesis of pyrimidine nucleotides, the degradative processing of peptides and proteins, oxidative stress damage and purine salvage and nucleotide synthesis and metabolism. …”
    Get full text
    info:eu-repo/semantics/article
  4. 4
    Microsatellite Loci in the Gypsophyte Lepidium subulatum (Brassicaceae), and Transferability to Other Lepidieae
    “…Using 454 pyrosequencing 12 microsatellite loci including di- and tri-nucleotide repeats were characterized in L. subulatum. …”
    Get full text
    info:eu-repo/semantics/article
  5. 5
    Epigenetic biomarkers in obesity, weight loss and inflammation: a role for circadian rhythm and methyl donors
    “…Epigenetics refers to all the modifications that alter gene activity without nucleotide sequence modification, but including the chromatin structure alteration as a direct consequence. …”
    Get full text
    info:eu-repo/semantics/doctoralThesis
  6. 6
    Evaluation of the effects of erythritol on gene expression in Brucella abortus
    “…On the other hand, several routes of amino acid and nucleotide biosynthesis are up-regulated whilst amino acid transport and catabolism genes are down-regulated. …”
    Get full text
    info:eu-repo/semantics/article
  7. 7
    Estrategias para la detección y caracterización funcional de nuevas translocaciones cromosómicas en cáncer
    “…Although several studies have shown the role of nucleotide motifs and local characteristics of the sequences as the cause of such non-random distribution, the relevance of the functional factors in defining the position of the breakpoints involved in chromosomal translocations has not yet been tested experimentally. …”
    Get full text
    info:eu-repo/semantics/doctoralThesis
  8. 8
    Dose-finding study and pharmacogenomic analysis of fixed-rate infusion of gemcitabine, irinotecan and bevacizumab in pretreated metastatic colorectal cancer patients
    “…Pharmacogenomic analysis was performed to investigate the association between VEGF single-nucleotide polymorphisms and clinical outcome. PATIENTS AND METHODS: A total of 89 mCRC patients were recruited in a two-step study design; 28 were included in the dose-finding study and 59 in the pharmacogenomic analysis. …”
    Get full text
    info:eu-repo/semantics/article
  9. 9
    Estudio multicéntrico del marcador genético rs12536657 del gen HGF y parámetros biométricos oculares en niños hipermétropes respecto a adolescentes y adultos jóvenes emétropes
    “…La primera asociación genética para la hipermetropía se publicó en el 2010 por Veerappan que encontró una asociación entre los SNPs (Single Nucleotide Polymorphisms) rs12536657 y rs5745718 del gen HGF (factor de crecimiento hepatocitario) y la hipermetropía en un estudio de casos y controles en una población adulta australiana.…”
    Get full text
    info:eu-repo/semantics/doctoralThesis
  10. 10
    Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance
    “…Objective: To determine the association between endoplasmic reticulum aminopeptidase (ERAP)1 and ERAP2 single-nucleotide polymorphisms (SNPs) and human leukocyte antigens (HLA)-B27+ or HLA-B15+ patients with spondyloarthritis (SpA). …”
    Get full text
    info:eu-repo/semantics/article
  11. 11
    miRNAs as predictive biomarkers of obesity and weight loss: epigenetic regulation and target gene identification
    “…Epigenetics refers to molecular factors and processes around the DNA that regulate genome activity without nucleotide sequence modification. One of these epigenetic factors are miRNAs, a class of small (17-25 nts in length) single stranded non coding RNAs that post transcriptionally regulate gene expression in animals, plants and unicellular eukaryotes. …”
    Get full text
    info:eu-repo/semantics/doctoralThesis
  12. 12
    CLOCK gene variation is associated with incidence of type‑2 diabetes and cardiovascular diseases in type‑2 diabetic subjects: dietary modulation in the PREDIMED randomized trial
    “…Moreover, although in a previous work we detected a gene-diet interaction between the CLOCK-rs4580704 (C > G) single nucleotide polymorphism (SNP) and monounsaturated (MUFA) intake on insulin resistance, no interventional study has analyzed gene-diet interactions on T2D or CVD outcomes. …”
    Get full text
    info:eu-repo/semantics/article
  13. 13
    Influence of lifestyle on obesity and telomere length in a pediatric population and elderly subjects of the SUN project
    “…On the other hand, a healthy lifestyle change has been suggested to have impact on DNA damage markers, such as telomeres: repetitive nucleotide sequences (5 -TTAGGG-3 ) at the end of chromosomes providing stability and protection towards the genome. …”
    Get full text
    info:eu-repo/semantics/doctoralThesis
  14. 14
    Validación del ácido úrico como predictor de severidad en gestantes con trastornos hipertensivos del Hospital Vicente Corral Moscoso. Cuenca, 2020
    Get full text
    masterThesis
  15. 15
    Estandarización de la reacción en cadena de la polimerasa (PCR) específica para la amplificación del fragmento rs35532010 presente en el gen de la beta globina
    Get full text
  16. 16
    Nuevas aproximaciones terapéuticas para la Enfermedad de Alzheimer: inhibidores de PDE5
    “…It has even been suggested that an imbalance in the cyclic nucleotides signaling caused by an inadequate control by these enzymes may contribute to the synaptic deficits occurring in neurodegenerative disorders that curse with dementia. …”
    Get full text
    info:eu-repo/semantics/doctoralThesis
  17. 17
    Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens
    “…Instead, phenotypes are largely dictated by “off-target” effects resulting from partial complementarity of siRNAs to multiple mRNAs via the “seed” region (i.e., nucleotides 2–8), reminiscent of the way specificity is determined for endogenous microRNAs. …”
    Get full text
    info:eu-repo/semantics/article
  18. 18
    “Caracterización genética de gallos de pelea (Gallus gallus) del cantón Cuenca mediante mtDNA D-Loop.”
    Get full text
    bachelorThesis
Search Tools: RSS Feed – Email Search