by
Vilalta, A. (Anna),
Aldaz, A. (Azucena),
Sala-Elarre, P. (Pablo),
Urrizola-Martínez, A. (Amaia),
Chopitea, A. (Ana),
Arbea-Moreno, L. (Leire),
Rotellar, F. (Fernando),
Pardo, F. (Fernando),
Marti-Cruchaga, P. (Pablo),
Zozaya-Larequi, G. (Gabriel),
Subtil, J.C. (José Carlos),
Rodríguez-Rodríguez, J. (Javier),
Ponz-Sarvise, M. (Mariano)
Published 2023
“…Pharmacokinetic-guided (PKG) dosing has demonstrated beneficial effects in other
tumors, but scarce data is available in
pancreatic cancer.
Methods: Forty-six patients with resected PDAC after mFOLFIRINOX neoadjuvant approach and included
in an institutional protocol for anticancer drug monitoring were retrospectively analyzed. 5-Fluorouracil
(5-FU) dosage was adjusted throughout neoadjuvant treatment according to pharmacokinetic parameters and Irinotecan (CPT-11) pharmacokinetic variables were retrospectively estimated.
…”
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info:eu-repo/semantics/article