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2“…One of these substrains, the senescence-accelerated mouse prone-8 (SAMP8) strain manifests irreversible advancing senescence and shares similar characteristics with aged humans. …”
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3by Reboredo-Fuentes, C. (Cristian), Irache, J.M. (Juan Manuel), Gonzalez-Navarro, C.J. (Carlos Javier)“…The objective of the third chapter was to evaluate whether the hypoglycemic effect observed for orally administered empty nanoparticles could lead to some health benefits in two animal models: C. elegans and the senescence accelerated mouse prone-8 (SAMP8 mice). The supplementation of the growth medium of C. elegans with empty nanoparticles induced a significant increase in the lifespan of the worms. …”
Published 2022
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4by Janeiro-Arenas, M.H. (Manuel Humberto), Ramirez, M.J. (María Javier), Solas, M. (Maite)“…Moreover, TMAO was able to activate microglia and raise the expression of the pro-inflammatory marker CD16/CD32, increasing aberrantly myelin phagocytosis. SAMP8 a senescence accelerated mouse model was used to study the effect of aging (the main risk factor for AD) in peripheral inflammation and neuroinflammation. …”
Published 2023
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5by Alonso López, Laura“…It is involved in determining sex, maturation and senescence of the fruits, the epinastic curvatures of leaves and seed germination. …”
Published 2021
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