Small-molecule biodiscovery and pathway elucidation in zebrafish
La investigación biomédica y farmacológica se basa en el uso de métodos experimentales in vitro y estudios in vivo en modelos animales para analizar diversos aspectos involucrados en los procesos fisiopatológicos y para replicar enfermedades humanas. En particular, los modelos animales de experiment...
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| Médium: | Kniha |
| Jazyk: | English |
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Obsah:
- Background and rationale & general introduction
- Aims of the doctoral research project
- Optimization and pharmacological validation of an in vivo leukocyte migration assay in zabrafish larvae: Rapid evaluation of anti: inflammatory natural products
- Integration of microfractionation, qNMR and zebrafisch screening for the in vivo bioassayguided isolation and quantitative analysis of natural products
- etc.