Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice

Mutation A30P in the alpha-synuclein gene is a cause of familial Parkinson disease. Transgenic mice expressing wild mouse and mutant human A30P alpha-synuclein, Tg5093 mice (Tg), show a progressive motor disorder characterized by tremor, rigidity, and dystonia, accompanied by accumulation of alpha-s...

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Bibliographic Details
Main Authors: Dalfo, E. (Esther), Rosa, J.L. (J.L.), Cuadrado-Tejedor, M. (Mar), Ambrosio, S. (S.)
Format: info:eu-repo/semantics/article
Language:eng
Published: LIPPINCOTT WILLIAMS & WILKINS 2010
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Online Access:https://hdl.handle.net/10171/12341