New methodologies to characterize the effectiveness of the gene transfer mediated by DNA-chitosan nanoparticles

In this work three DNA-chitosan nanoparticle formulations (Np), differing in the molecular weight (MW; 150 kDa, 400 kDa, and 600 kDa) of the polysaccharide, were prepared and administered by two different administration routes: the hydrodynamics-based procedure and the intraduodenal injection. Af...

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Bibliographic Details
Main Authors: Centelles, M.N. (Miguel N.), Qian, C. (Cheng), Campanero, M.A. (Miguel Angel), Irache, J.M. (Juan Manuel)
Format: info:eu-repo/semantics/article
Language:eng
Published: Dove Medical Press Ltd. 2011
Subjects:
Online Access:https://hdl.handle.net/10171/17090