Nanosystems for the oral administration of alkyl-lysophospholipid anti-tumor agents: development of lipid nanotransporters and preclinical studies

Edelfosine is a synthetic alkyl ether phospholipid that represents a promising class of antitumor agents, with limited side effects but presenting a low oral bioavailability. In order to solve this drawback, edelfosine has been entrapped into lipid nanoparticles (LN). The nanosystems have been prep...

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Bibliographic Details
Main Authors: Estella-Hermoso-de-Mendoza, A. (Ander), Blanco-Prieto, M.J. (María José)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Servicio de Publicaciones de la Universidad de Navarra 2011
Subjects:
Online Access:https://hdl.handle.net/10171/17631