Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death

Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death

The antiphospholipid syndrome (APS) is associated with thrombosis and fetal death but the pathologic mechanisms are poorly understood. Since endothelial protein C receptor (EPCR) plays a role in the anticoagulant system and in placental development, we hypothesized that anti-EPCR autoantibodies may...

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Bibliographic Details
Main Authors: Hurtado, V. (Verónica), Montes, R. (Ramón), Gris, J.C. (Jean-Christophe), Bertolaccini, M.L. (María L.), Alonso, A. (Alvaro), Martinez-Gonzalez, M.A. (Miguel Ángel), Khamashta, M.A. (Munther A.), Fukudome, K. (Kenji), Lane, D.A. (David A.), Hermida, J. (José)
Format: info:eu-repo/semantics/article
Language:eng
Published: American Society of Hematology 2012
Subjects:
Antiphospholipid syndrome/immunology
Autoantibodies/blood
Endothelins/immunology
Fetal death/immunology
Pregnancy complications/immunology
Online Access:https://hdl.handle.net/10171/22273

Internet

https://hdl.handle.net/10171/22273

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