Quantitative determination of the antitumor alkyl ether phospholipid edelfosine by reversed-phase liquid chromatography-electrospray mass spectrometry: application to cell uptake studies and characterization of drug delivery systems.
Edelfosine is a synthetic alkyl ether phospholipid that represents a promising class of antitumor agents. However, analytical methods to measure these type compounds are scarce. The lack of a reliable methodology to quantify edelfosine is a major problem in ongoing and scheduled preclinical and clin...
Main Authors: | , , |
---|---|
Format: | info:eu-repo/semantics/article |
Language: | eng |
Published: |
Elsevier
2012
|
Subjects: | |
Online Access: | https://hdl.handle.net/10171/22385 |