Quantitative determination of the antitumor alkyl ether phospholipid edelfosine by reversed-phase liquid chromatography-electrospray mass spectrometry: application to cell uptake studies and characterization of drug delivery systems.

Edelfosine is a synthetic alkyl ether phospholipid that represents a promising class of antitumor agents. However, analytical methods to measure these type compounds are scarce. The lack of a reliable methodology to quantify edelfosine is a major problem in ongoing and scheduled preclinical and clin...

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Bibliographic Details
Main Authors: Blanco-Prieto, M.J. (María José), Campanero, M.A. (Miguel Angel), Mollinedo, F. (Faustino)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2012
Subjects:
Online Access:https://hdl.handle.net/10171/22385