Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/PLGA microspheres.
The aim of the work was to develop biodegradable microspheres for controlled delivery of the somatostatin analogue vapreotide and maintenance of sustained plasma levels over 2–4 weeks after a single injection in rats. Vapreotide was microencapsulated into end-group capped and uncapped low molecular...
| Main Authors: | , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
| Published: |
Elsevier
2012
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/22386 |