Development and validation of a liquid chromatographic method for in vitro mupirocin quantification in both skin layers and percutaneous penetration studies.

A simple, rapid, and sensitive reversed-phase high-performance liquid chromatographic (HPLC) method for the measurement of mupirocin concentrations in both skin layers and percutaneous samples has been developed. Mupirocin was extracted from skin layers using PBS–acetonitrile (90:10, v/v). The metho...

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Bibliographic Details
Main Authors: Echevarría, L. (Lydia), Blanco-Prieto, M.J. (María José), Campanero, M.A. (Miguel Angel), Santoyo, S. (Susana)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2012
Subjects:
Online Access:https://hdl.handle.net/10171/22388