DNA polymorphism analysis of Brucella lipopolysaccharide genes reveals marked differences in O-polysaccharide biosynthetic genes between smooth and rough Brucella species and novel species-specific markers

Background: The lipopolysaccharide is a major antigen and virulence factor of Brucella, an important bacterial pathogen. In smooth brucellae, lipopolysaccharide is made of lipid A-core oligosaccharide and N-formylperosamine O-polysaccharide. B. ovis and B. canis (rough species) lack the O-polysaccha...

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Bibliographic Details
Main Authors: Zygmunt, M. (Michel), Blasco, J.M. (J. M.), Letesson, J.J. (Jean Jacques), Cloeckaert, A. (Axel), Moriyon, I. (Ignacio)
Format: info:eu-repo/semantics/article
Language:eng
Published: BioMed Central 2013
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Online Access:https://hdl.handle.net/10171/29418