New antiseptic peptides to protect against endotoxin-mediated shock

New antiseptic peptides to protect against endotoxin-mediated shock

Systemic bacterial infections are associated with high mortality. The access of bacteria or constituents thereof to systemic circulation induces the massive release of immunomodulatory mediators, ultimately causing tissue hypoperfusion and multiple-organ failure despite adequate antibiotic treatment...

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Bibliographic Details
Main Authors: Gutsmann, T. (Thomas), Razquin-Olazaran, I. (Iosu), Kowalski, I. (Ina), Kaconis, Y. (Yani), Howe, J. (Jörg), Bartels, R. (Rainer), Hornef, M. (Mathias), Schürholz, T. (Tobias), Rossle, M. (Manfred), Sánchez-Gómez, S. (Susana), Moriyon, I. (Ignacio), Martinez-de-Tejada, G. (Guillermo), Brandenburg, K. (Klaus)
Format: info:eu-repo/semantics/article
Language:eng
Published: American Society for Microbiology 2013
Subjects:
Antimicrobial peptide
Escherichia coli
In vitro
Lipid A
Lipopolysaccharide
Neutralization
Sepsis
Detoxification
Antibacterial
Binding
Online Access:https://hdl.handle.net/10171/29492

Internet

https://hdl.handle.net/10171/29492

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