Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis

Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis

This study extends earlier reports regarding the in vitro efficacies of the 1,4-di-N-oxide quinoxaline derivatives against Mycobacterium tuberculosis and has led to the discovery of a derivative with in vivo efficacy in the mouse model of tuberculosis. Quinoxaline-2-carboxylate 1,4-di-N-oxide deriva...

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Detalhes bibliográficos
Principais autores: Vicente, E. (Esther), Raquel, Burguete, A. (Asunción), Solano, B. (Beatriz), Pérez-Silanes, S. (Silvia), Aldana, I. (Ignacio), Maddry, J.A. (Joseph A.), Lenaerts, A.J. (Anne J.), Franzblau, S.G. (Scott G.), Cho, S.H. (Sang-Hyun), Monge, A. (Antonio), Goldman, R.C. (Robert C.)
Formato: info:eu-repo/semantics/article
Idioma:eng
Publicado em: American Society for Microbiology 2013
Assuntos:
Cyclic N-oxides
Antitubercular agents
Mycobacterium tuberculosis
Quinoxalines
Acesso em linha:https://hdl.handle.net/10171/29497

Internet

https://hdl.handle.net/10171/29497

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