Characterization of Brucella abortus O-polysaccharide and core lipopolysaccharide mutants and demonstration that a complete core is required for rough vaccines to be efficient against Brucella abortus and Brucella ovis in the mouse model

Brucella abortus rough lipopolysaccharide (LPS) mutants were obtained by transposon insertion into two wbk genes (wbkA [putative glycosyltransferase; formerly rfbU] and per [perosamine synthetase]), into manB (pmm [phosphomannomutase; formerly rfbK]), and into an unassigned gene. Consistent with gen...

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Detalles Bibliográficos
Main Authors: Monreal, D. (Daniel), Grillo, M.J. (María Jesús), González-Fernández, D. (David), Marin, C.M. (C. M.), Miguel, M.J. (María Jesús) de, Lopez-Goñi, I. (Ignacio), Blasco, J.M. (J. M.), Cloeckaert, A. (Axel), Moriyon, I. (Ignacio)
Formato: info:eu-repo/semantics/article
Idioma:eng
Publicado: American Society for Microbiology 2013
Subjects:
Acceso en liña:https://hdl.handle.net/10171/29521