Structural features governing the activity of lactoferricin-derived peptides that act in synergy with antibiotics against Pseudomonas aeruginosa in vitro and in vivo

Structural features governing the activity of lactoferricin-derived peptides that act in synergy with antibiotics against Pseudomonas aeruginosa in vitro and in vivo

Pseudomonas aeruginosa is naturally resistant to many antibiotics, and infections caused by this organism are a serious threat, especially to hospitalized patients. The intrinsic low permeability of P. aeruginosa to antibiotics results from the coordinated action of several mechanisms, such as the p...

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Bibliographic Details
Main Authors: Sánchez-Gómez, S. (Susana), Japelj, B. (Bostjan), Jerala, R. (Roman), Moriyon, I. (Ignacio), Fernández-Alonso, M. (Miriam), Leiva, J. (José), Blondelle, S.E. (Sylvie E.), Andrä, J. (Jörg), Brandenburg, K. (Klaus), Lohner, K. (Karl), Martinez-de-Tejada, G. (Guillermo)
Format: info:eu-repo/semantics/article
Language:eng
Published: American Society for Microbiology 2013
Subjects:
Anti-Bacterial Agents pharmacology
Anti-Bacterial Agents therapeutic use
Lactoferrin chemistry
Peptides pharmacology
Peptides therapeutic use
Pseudomonas Infections drug therapy
Pseudomonas aeruginosa drug effects
Female
Online Access:https://hdl.handle.net/10171/29639

Internet

https://hdl.handle.net/10171/29639

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