New antagonist agents of Neuropeptide Y receptors

In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as ant...

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Príomhchruthaitheoirí: Aldana, I. (Ignacio), Rivero, I. (Isabel), Rivero, A. (Argimiro), Huenchuñir, P. (Patricio), Frigola, C. (Carmen), Alonso, M.L. (María Luisa), Monge, A. (Antonio)
Formáid: info:eu-repo/semantics/article
Teanga:eng
Foilsithe / Cruthaithe: Sociedade Brasileira de Química 2013
Ábhair:
Rochtain ar líne:https://hdl.handle.net/10171/29641
Cur síos
Achoimre:In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.