Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin

Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin

OBJECTIVES: The aim of this study was to investigate different hydrophobic gentamicin formulations [gentamicin-bis(2-ethylhexyl) sulfosuccinate (GEN-AOT), microstructured GEN-AOT (PCA GEN-AOT) and GEN-AOT-loaded poly(lactide-co-glycolide) acid (PLGA) nanoparticles (NPs)] in view of improving its the...

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Bibliographic Details
Main Authors: Imbuluzqueta, E. (Edurne), Lemaire, S. (Sandrine), Gamazo, C. (Carlos), Elizondo, E. (Elisa), Ventosa, N. (Nora), Veciana, J. (Jaume), Van-Bambeke, F. ( Françoise), Blanco-Prieto, M.J. (María José)
Format: info:eu-repo/semantics/article
Language:eng
Published: Oxford University Press 2013
Subjects:
Gentamicin
Nanoparticles
Intracellular bacteria
Drug accumulation
Subcellular distribution
Online Access:https://hdl.handle.net/10171/29642

Internet

https://hdl.handle.net/10171/29642

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