Randomized pharmacokinetic study comparing subcutaneous and intravenous palonosetron in cancer patients treated with platinum based chemotherapy

BACKGROUND: Palonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though it could have useful clinical applicatio...

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Main Authors: Sadaba, B. (Belén), Barrio, A. (Anabel) del, Campanero, M.A. (Miguel Angel), Azanza, J.R. (José Ramón), Gomez-Guiu, A. (Almudena), Lopez-Picazo, J.M. (José M.), Martin-Algarra, S. (Salvador), Guillen-Grima, F. (Francisco), Blanco-Prieto, M.J. (María José), Perez-Gracia, J.L. (Jose Luis), Gurpide, A. (Alfonso)
Format: info:eu-repo/semantics/article
Language:eng
Published: Public Library of Science 2014
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Online Access:https://hdl.handle.net/10171/35520