Synthesis, biological evaluation and structure-activity relationships of new quinoxaline derivatives as anti-Plasmodium falciparum agents
We report the synthesis and antimalarial activities of eighteen quinoxaline and
quinoxaline 1,4-di-N-oxide derivatives, eight of which are completely novel. Compounds
1a and 2a were the most active against Plasmodium falciparum strains. Structure-activity relationships demonstrated the importance...
Full description
Bibliographic Details
| Main Authors: |
Aldana, I. (Ignacio),
Monge, A. (Antonio),
Deharo, E. (Eric),
Pérez-Silanes, S. (Silvia),
Burguete, A. (Asunción),
Galiano, S. (Silvia),
Pabon, A. (Adriana),
Gil, A. (Ana) |
|---|
| Format: | info:eu-repo/semantics/article
|
|---|
| Language: | eng |
|---|
| Published: |
MDPI (Molecular Diversity Preservation International)
2014
|
|---|
| Subjects: | |
|---|
| Online Access: | https://hdl.handle.net/10171/35725
|
|---|