Synthesis, biological evaluation and structure-activity relationships of new quinoxaline derivatives as anti-Plasmodium falciparum agents
We report the synthesis and antimalarial activities of eighteen quinoxaline and quinoxaline 1,4-di-N-oxide derivatives, eight of which are completely novel. Compounds 1a and 2a were the most active against Plasmodium falciparum strains. Structure-activity relationships demonstrated the importance...
| المؤلفون الرئيسيون: | , , , , , , , |
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| التنسيق: | info:eu-repo/semantics/article |
| اللغة: | eng |
| منشور في: |
MDPI (Molecular Diversity Preservation International)
2014
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://hdl.handle.net/10171/35725 |