New quinoxaline 1,4-di-N-oxide derivatives: Trypanosomaticidal activities and enzyme docking simulation

New quinoxaline 1,4-di-N-oxide derivatives: Trypanosomaticidal activities and enzyme docking simulation

Two series of pyrazol and propenone quinoxaline derivatives were tested for parasiticidal activity (against amastigotes of Leishmania peruviana and trypomastigotes of Trypanosoma cruzi) and for toxicity against proliferative and non-proliferative cells. The pyrazol series was almost inactive against...

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Bibliographic Details
Main Authors: Estevez, Y. (Yannick), Quiliano, M. (Miguel), Burguete, A. (Asunción), Cabanillas, B. (Billy), Zimic, M. (Mirko), Malaga, E. (Edith), Verastegui, M. (Manuela), Pérez-Silanes, S. (Silvia), Aldana, I. (Ignacio), Monge, A. (Antonio), Castillo, D. (Denis), Deharo, E. (Eric)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2014
Subjects:
Quinoxaline
Leishmania peruviana
Trypanosoma cruzi
Online Access:https://hdl.handle.net/10171/35791

Internet

https://hdl.handle.net/10171/35791

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