Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents

Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents

As a continuation of our research and with the aim of obtaining new agents against Chagas disease, an extremely neglected disease which threatens 100 million people, eighteen new quinoxaline 1,4-di-Noxide derivatives have been synthesized following the Beirut reaction. The synthesis of the new deri...

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Hlavní autoři: Pérez-Silanes, S. (Silvia), Monge, A. (Antonio), Aldana, I. (Ignacio), Gonzalez, M. (Mercedes), Cerecetto, H. (Hugo), Di-Maio, R. (Rossanna), Birriel, E. (Estefanía), Varela, J. (Javier), Arbillaga, L. (Leire), Azqueta, A. (Amaya), Crawford, P.W. (Philip W.), Devarapally, G. (Goutham), Galiano, S. (Silvia), Moreno-de-Viguri, E. (Elsa), Torres, E. (Enrique)
Médium: info:eu-repo/semantics/article
Jazyk:eng
Vydáno: Elsevier 2014
Témata:
Reduction potential
Cytotoxicity
Mutagenicity
Quinoxaline 1,4-di-N-oxide
Trypanosoma cruzi
Chagas disease
On-line přístup:https://hdl.handle.net/10171/35794

Internet

https://hdl.handle.net/10171/35794

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