Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

Systematic genetic perturbation screening in human cells remains technically challenging. Typically, large libraries of chemically synthesized siRNA oligonucleotides are used, each designed to degrade a specific cellular mRNA via the RNA interference (RNAi) mechanism. Here, we report on data from th...

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Bibliographic Details
Main Authors: Franceschini, A. (Andrea), Meier, R. (Roger), Casanova, A. (Alain), Kreibich, S. (Saskia), Daga, N. (Neha), Andritschke, D. (Daniel), Dilling, S. (Sabrina), Rämö, P. (Pauli), Emmenlauer, M. (Mario), Kaufmann, A. (Andreas), Raquel, Low, S.H. (Shyan Huey), Pelkmans, L. (Lucas), Helenius, A. (Ari), Hardt, W.D. (Wolf Dietrich), Dehio, C. (Christoph), Mering, C. (Christian) von
Format: info:eu-repo/semantics/article
Language:eng
Published: National Academy of Sciences 2014
Subjects:
High-throughput RNAi screening
Antimicrobials
Online Access:https://hdl.handle.net/10171/35828

Internet

https://hdl.handle.net/10171/35828

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