Contribution of the GATA2 transcription factor to the development and progression of myeloid disorders

The GATA2 transcription factor has an essential role in the proliferation and differentiation of hematopoietic cells. GATA2 contributes to myeloid malignancies through various mechanisms, including GATA2 overexpression in acute myeloid leukemia (AML), somatic GATA2 mutations in chronic myeloid leuke...

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Bibliographic Details
Main Authors: Cortes-Lavaud, X. (Xabier), Odero, M.D. (Maria Dolores)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Servicio de Publicaciones de la Universidad de Navarra 2014
Subjects:
Online Access:https://hdl.handle.net/10171/37151