Evaluation and optimization of immunomagnetic methods for the purification and selection of CMV-specific cytotoxic T lymphocytes from G-CSF primed peripheral blood mononuclear cells for adoptive immunotherapy

Adoptive transfer of cytomegalovirus (CMV)-specific T cells has shown promising results in preventing pathological effects caused by opportunistic CMV infection in patients following allogeneic hematopoietic stem cell transplantation. The majority of studies have used steady-state leukapheresis for...

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Bibliographic Details
Main Authors: Beloki, L. (Lorea), Olavarría, E. (Eduardo), Ramirez, N. (Natalia)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Servicio de Publicaciones de la Universidad de Navarra 2015
Subjects:
Online Access:https://hdl.handle.net/10171/38528