Role of homeobox NKX2-3 protein in marginal-zone B-cell lymphomagenesis using an in vivo mouse model

NKX2 homeobox family proteins play a role in cancer development. Molecular cloning of a translocation t(10;14)(q24;q32) from a marginal-zone B-cell lymphoma revealed NKX2-3 as an IGH partner gene, leading to increased NKX2-3 expression with respect to B lymphocytes. NKX2-3 overexpression was also de...

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Bibliographic Details
Main Authors: Mena-Varas, M. (María), Martinez-Climent, J.A. (José Ángel), Robles, E.F. (Eloy Francisco)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10171/39773