Design and synthesis of novel quinoxaline derivatives as potential candidates for treatment of multidrug-resistant and latent tuberculosis

Abstract Twenty-four quinoxaline derivatives were evaluated for their antimycobacterial activity using BacTiter-Glo microbial cell viability assay. Five compounds showed MIC values < 3.1 μM and IC50 values < 1.5 μM in primary screening and therefore, they were moved on for further evaluati...

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Bibliographic Details
Main Authors: Santivañez-Veliz, M. (Mery), Pérez-Silanes, S. (Silvia), Torres, E. (Enrique), Moreno-de-Viguri, E. (Elsa)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2016
Subjects:
Online Access:https://hdl.handle.net/10171/40412