Novel targeted polyamidoamine (PAMAM) nanocarriers for gene delivery: design, development and evaluation

In this work, different targeted formulations have been designed and evaluated in order to improve gene delivery to cancer cells by non-viral vectors in vitro and in vivo. All the nanosystems are based on the dendrimeric carrier PAMAM, to which four different ligands (hyaluronic acid, transferrin...

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Bibliographic Details
Main Authors: Urbiola-Perez, K. (Koldo), Tros-de-Ilarduya, C. (Conchita)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10171/40600