Novel targeted polyamidoamine (PAMAM) nanocarriers for gene delivery: design, development and evaluation
In this work, different targeted formulations have been designed and evaluated in order to improve gene delivery to cancer cells by non-viral vectors in vitro and in vivo. All the nanosystems are based on the dendrimeric carrier PAMAM, to which four different ligands (hyaluronic acid, transferrin...
Main Authors: | , |
---|---|
Format: | info:eu-repo/semantics/doctoralThesis |
Language: | eng |
Published: |
2016
|
Subjects: | |
Online Access: | https://hdl.handle.net/10171/40600 |