Characterization of cellular and molecular responses of human glioblastoma to Transforming Growth Factor-β signalling pathway inhibition
Glioblastoma Multiforme (GBM) is the most prevalent malignant brain tumour accounting for 60-70% of all gliomas. Improvements in survival over the past 100 years can be measured only in weeks, and current achieved median survival ranges only 12-15 months. A hallmark of this malignancy is the intr...
Main Authors: | , , |
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Format: | info:eu-repo/semantics/doctoralThesis |
Language: | eng |
Published: |
2016
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Subjects: | |
Online Access: | https://hdl.handle.net/10171/41418 |