Characterization of cellular and molecular responses of human glioblastoma to Transforming Growth Factor-β signalling pathway inhibition

Glioblastoma Multiforme (GBM) is the most prevalent malignant brain tumour accounting for 60-70% of all gliomas. Improvements in survival over the past 100 years can be measured only in weeks, and current achieved median survival ranges only 12-15 months. A hallmark of this malignancy is the intr...

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Bibliographic Details
Main Authors: Gallo, G.O. (Gabriel Osvaldo), Dotor, J. (Javier), Saez-Castresana, J. (Javier)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10171/41418