Characterization of cellular and molecular responses of human glioblastoma to Transforming Growth Factor-β signalling pathway inhibition

Characterization of cellular and molecular responses of human glioblastoma to Transforming Growth Factor-β signalling pathway inhibition

Glioblastoma Multiforme (GBM) is the most prevalent malignant brain tumour accounting for 60-70% of all gliomas. Improvements in survival over the past 100 years can be measured only in weeks, and current achieved median survival ranges only 12-15 months. A hallmark of this malignancy is the intr...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Gallo, G.O. (Gabriel Osvaldo), Dotor, J. (Javier), Saez-Castresana, J. (Javier)
Format:	info:eu-repo/semantics/doctoralThesis
Sprog:	eng
Udgivet:	2016
Fag:	Brain tumour Glioblastoma multiforme Materias Investigacion::Ciencias de la Salud
Online adgang:	https://hdl.handle.net/10171/41418

Lignende værker

Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
af: Schalper, K.A. (Kurt A.), et al.
Udgivet: (2024)

Reaction network analysis in biochemical signaling pathways
af: Martinez-Forero, I. (Iván), et al.
Udgivet: (2010)

Gliosarcoma /
af: Encalada G., Verónica

Gliosarcoma /
af: Encalada G., Verónica

Gliosarcoma /
af: Encalada G., Verónica

Gliosarcoma /
af: Encalada G., Verónica

A study of brain drain from the perspective of salvadorans living in Pamplona, Spain
af: Benítez-Chávez, M.J. (María José), et al.
Udgivet: (2018)

Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8
af: Andrea, C.E. (Carlos Eduardo) de, et al.
Udgivet: (2021)

Comparison between Three Therapeutic Options for the Treatment of Balance and Gait in Stroke: A Randomized Controlled Trial
af: Pérez de la Cruz, Sagrario
Udgivet: (2021)

Programa de tratamiento de fisioterapia en un traumatismo craneoencefálico. Caso clínico
af: Aguilera Luiz, Beatriz
Udgivet: (2015)

Neuroendocrinology and brain peptides

Implementation of a model for detection and classification of brain tumours in magnetic resonance imaging using convolutional neural networks
af: Serra-Parri, A. (Alvaro), et al.
Udgivet: (2023)

Propuesta de intervención y rehabilitación neuropsicológica en daño cerebral sobrevenido: caso clínico tras un traumatismo craneoencefálico.
af: Quiñones Carbajo, Vanessa
Udgivet: (2015)

Systematic analysis of the novel effectors PITPNC1 and HMGCS1 in mutant KRAS tumours
af: Entrialgo-Cadierno, R. (Rodrigo), et al.
Udgivet: (2023)

Immuno-virotherapy for glioblastoma: Characterization of Delta 24-ACT in combination with different immunomodulators as therapeutic approach
af: Puigdelloses-Vallcorba, M. (Montserrat), et al.
Udgivet: (2021)

TIM-3 blockade as a therapeutic approach for diffuse intrinsic pontine glioma
af: Ausejo-Mauleón, I. (Iker), et al.
Udgivet: (2024)

The Effect of Multiprobiotics on Memory and Attention in Fibromyalgia: A Pilot Randomized Controlled Trial
af: Cardona, Diana, et al.
Udgivet: (2021)

Limiti e Classificazione del Nuovo Campo della Neuroetica: Identitá, Responsabilitá, Informazione e Manipolazione del Cervello
af: Echarte-Alonso, L.E. (Luis Enrique)
Udgivet: (2013)

Cellular immunology /
af: Macfarlane Burnet, Frank. 1899-1985
Udgivet: (1969)

Estudio de la cognición social en daño cerebral a partir de una prueba ecológica: MASC
af: Ganivet Pérez, Alba
Udgivet: (2019)

Dermatología pediátrica II

Effects of dexmedetomidine on subthalamic local field potentials in parkinson's disease
af: Martinez-Simon, A. (Antonio), et al.
Udgivet: (2022)

Development of methodology for the characterisation and modelling of soft tissues for real-time simulation. Application to the modelling of the viscoelastic mechanical response of brain tissue.
af: Mendizabal-Dones, A. (Ainhitze), et al.
Udgivet: (2015)

Pathways to good english

Development of three-dimensional biomaterials containing stem cells and neurotrophic factors for brain repair in Parkinson's disease
af: Torres-Ortega, P.V. (Pablo Vicente), et al.
Udgivet: (2022)

Permeability enhancers sensitize β-lactamase-expressing Enterobacteriaceae and Pseudomonas aeruginosa to β-lactamase inhibitors, thereby restoring their β-lactam susceptibility
af: Ferrer-Espada, R. (Raquel), et al.
Udgivet: (2024)

Dietary tryptophan depletion alters the faecal bacterial community structure of compulsive drinker rats in schedule-induced polydipsia
af: Merchán Carrillo, Ana María, et al.
Udgivet: (2024)

Challenges and novel opportunities of radiation therapy for brain metastases in non-small cell lung cancer
af: Jablonska, P.A. (Paola Anna), et al.
Udgivet: (2022)

Cellular biology nucleic acids and viruses /
Udgivet: (1957)

Characterization of Cross-Linked Enzyme Aggregates of the Y509E Mutant of a Glycoside Hydrolase Family 52 β-xylosidase from G. stearothermoph
af: Romero, Gabriela, et al.
Udgivet: (2021)

Intervención ecológica basada en la motivación del paciente con afasia: estudio de un caso clínico
af: Velasco Collado, Yael N.
Udgivet: (2019)

Photosynthesis Inhibiting Effects of Pesticides on Sweet Pepper Leaves
af: Giménez Moolhuyzen, Miguel, et al.
Udgivet: (2020)

Impact of astrocytic GLUT1 ablation on glucose homeostasis and cognition
af: García-Ardanaz, C. (Carlos), et al.
Udgivet: (2023)

Microstructural characterization and transformation kintetiks of austempered bearing steels.=Austenperizatutako errodamendutarako altzairuen mikroegituraren karakterizazioa eta eraldaketa zinetikak
af: Aramburu-Iztueta, A.(Ane), et al.
Udgivet: (2016)

Intervención sobre Inteligencia Animal en horas de guardia
af: Domínguez Pérez, Ana
Udgivet: (2022)

Adaptive Transformation for Architectural Models
af: Rodríguez-Gracia, Diego, et al.
Udgivet: (2020)

The cellular prion protein and its role in Alzheimer disease
af: Velayos, J.L. (José Luis), et al.
Udgivet: (2010)

Small-molecule biodiscovery and pathway elucidation in zebrafish
af: Cordero Maldonado, María Lorena

Pathways to probability: history of the mathematics of certainty and chance
af: King, Amy C.Read, Cecil B.

Enzyme promiscuity approaches to predict metabolic pathways in the human gut microbiota.
af: Balzerani, F. (Francesco), et al.
Udgivet: (2023)