Polymorphism of the transcription factor 7-like 2 gene (TCF7L2) interacts with obesity on type-2 diabetes in the PREDIMED study emphasizing the heterogeneity of genetic variants in type-2 diabetes risk prediction: time for obesity-specific genetic risk scores

Polymorphism of the transcription factor 7-like 2 gene (TCF7L2) interacts with obesity on type-2 diabetes in the PREDIMED study emphasizing the heterogeneity of genetic variants in type-2 diabetes risk prediction: time for obesity-specific genetic risk scores

Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by obesity. Moreover, TCF7L2-rs7903146 is one of the most influential varian...

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Bibliographic Details
Main Authors: Ordovas, J.M. (Jose Maria), Ros, E. (Emilio), Fito, M. (Montserrat), Basora, J. (Josep), Diez-Espino, J. (Javier), Fiol, M. (Miquel), Portoles, O. (Olga), Gomez-Gracia, E. (Enrique), Serra-Majem, L. (Luis), Ortega-Calvo, M. (Manuel), Martinez-Gonzalez, M.A. (Miguel Ángel), Quiles, L. (Laura), Estruch, R. (Ramón), Sorli, J.V. (Jose V.), Coltell, O. (Oscar), Corella, D. (Dolores)
Format: info:eu-repo/semantics/article
Language:spa
Published: MDPI 2017
Subjects:
PREDIMED study
TCF7L2-predictive value
T2D-genetic risk scores
Obesity
Type-2 diabetes
TCF7L2
Materias Investigacion::Ciencias de la Salud::Salud pública
Online Access:https://hdl.handle.net/10171/43266

Internet

https://hdl.handle.net/10171/43266

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