HDAC5 y SIRT2, dos dianas farmacológicas implicadas en el fenotipo depresivo y en la acción antidepresiva

Depression is a chronic disabling disorder mainly characterized by anhedonia and depressed mood, and still unresolved in terms of aetiology and response to treatment. Growing evidence suggests that epigenetic mechanisms play a key role in neuronal plasticity, and, therefore, mediate stable functiona...

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Bibliographic Details
Main Authors: Erburu-Calvo, M. M. (Mercedes Micaela), Tordera, R.M. (Rosa María), Puerta, E. (Elena)
Format: info:eu-repo/semantics/doctoralThesis
Language:spa
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10171/43583