rAAV8-mediated in vivo reprogramming of striatal astrocytes into neurons as a potential therapeutic strategy for neurodegenerative diseases

rAAV8-mediated in vivo reprogramming of striatal astrocytes into neurons as a potential therapeutic strategy for neurodegenerative diseases

CNS neurodegenerative disorders represent a major health problem worldwide. In PD, the progressive loss of miDA neurons leads to an irreversible dopamine deficiency in the striatum, ultimately triggering the appearance of the cardinal motor symptoms that typically characterize this movement disorder...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Pignataro, D. (Diego), González-Aseguinolaza, G. (Gloria), Lanciego, J.L. (José Luis)
פורמט: info:eu-repo/semantics/doctoralThesis
שפה:eng
יצא לאור: 2018
נושאים:
neurodegenerative diseases
Parkinson
gene therapy
Materias Investigacion::Ciencias de la Salud::Enfermedades y ataques cerbrovasculares
גישה מקוונת:https://hdl.handle.net/10171/50966

אינטרנט

https://hdl.handle.net/10171/50966

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