Effect of hypoxia on caveolin-1 expression, caveolae structure and insulin signaling

Obesity courses with the hypertrophy and hyperplasia of adipose tissue, which has been related to the development of hypoxia and, as consequence, insulin resistance. In this sense, insulin receptor is enriched in a specialized invagination of the plasma membrane named caveolae. Caveolin-1 (Cav-1) is...

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Bibliographic Details
Main Authors: Varela-Guruceaga, M. (Maider), Miguel-Vázquez, C. (Carlos) de, Milagro-Yoldi, F.I. (Fermín Ignacio)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10171/56365