Effect of hypoxia on caveolin-1 expression, caveolae structure and insulin signaling

Obesity courses with the hypertrophy and hyperplasia of adipose tissue, which has been related to the development of hypoxia and, as consequence, insulin resistance. In this sense, insulin receptor is enriched in a specialized invagination of the plasma membrane named caveolae. Caveolin-1 (Cav-1) is...

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Hlavní autoři: Varela-Guruceaga, M. (Maider), Miguel-Vázquez, C. (Carlos) de, Milagro-Yoldi, F.I. (Fermín Ignacio)
Médium: info:eu-repo/semantics/doctoralThesis
Jazyk:eng
Vydáno: 2019
Témata:
On-line přístup:https://hdl.handle.net/10171/56365