Design, synthesis and biological evaluation of novel methyl selenoesters as antiproliferative and cytotoxic agents
In this work, an innovative series of methylselenoesters as methylselenol precursors has been designed, synthesized and evaluated. The chemical characteristics of the carbonyl-selenium bond allow a nucleophilic attack that can render methylselenol, a key molecule in selenium biological activity. The...
| Main Authors: | , , |
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| Format: | info:eu-repo/semantics/doctoralThesis |
| Language: | eng |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/56406 |