ICAM-1-LFA-1 dependent CD8+ T-Lymphocyte aggregation in tumor tissue prevents recirculation to draining lymph nodes

ICAM-1-LFA-1 dependent CD8+ T-Lymphocyte aggregation in tumor tissue prevents recirculation to draining lymph nodes

The quantity of T-lymphocytes reaching the draining lymph nodes from tumors is likely important to mount effective distant responses and for the establishment of long term systemic memory. Looking into mechanisms behind lymphocyte egress, we directed our attention to leukocyte adhesion mechanisms...

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Bibliographic Details
Main Authors: Yanguas, A. (Alba), Garasa, S. (Saray), Teijeira, A. (Álvaro), Auba, C. (Cristina), Melero, I. (Ignacio), Rouzaut, A. (Ana)
Format: info:eu-repo/semantics/article
Language:eng
Published: Frontiers Media 2019
Subjects:
Draining lymph nodes
T-lymphocyte
Homotypic cell-adhesion
ICAM-1
Immune response
Cancer immunotherapy
Online Access:https://hdl.handle.net/10171/56647

Internet

https://hdl.handle.net/10171/56647

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