On the hipoxia regulation of CD137 and CD69 expression
The tumor microenvironment is characterized to be under severe conditions (nutrient shortage, low pH and oxygen deprivation) that affect not only tumor cells but also stroma and immune infiltrate. Tumor cells have developed mechanism in order to adapt their biology to such extreme circumstances. One...
| Main Authors: | , |
|---|---|
| Format: | info:eu-repo/semantics/doctoralThesis |
| Language: | eng |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/58001 |