Evaluation of skin permeation and retention of topical dapsone in murine cutaneous leishmaniasis lesions
The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated this drug for the topical treatment of CL. As efficacy depends on potency and skin penetration, we first det...
Main Authors: | Espuelas, S. (Socorro), Irache, J.M. (Juan Manuel), Sanmartin-Grijalba, C. (Carmen), Gonzalez-Peñas, E. (Elena), Navarro-Blasco, I. (Iñigo), Schwartz, J. (Juana), Calvo-Bacaicoa, A. (Alba), Moreno-Amatria, E. (Esther) |
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Format: | info:eu-repo/semantics/article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10171/58480 |
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